Osawa T, Akino T, Obika S. Synthesis, Duplex-Forming Ability, and Enzymatic Stability of Oligonucleotides Modified with Amide-Linked Dinucleotides Containing a 3′,4′-Tetrahydropyran-Bridged Nucleic Acid. J Org Chem. 2024 Jan 5;89(1):269-280. doi: 10.1021/acs.joc.3c02019.
Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways.Commun Biol.Ritsuko Suyama, Nicolas Cetraro, Joanne Y Yew, Toshie Kai.2023 Dec 20;6(1):1287. doi:10.1038/s42003-023-05660-x.
Ishida K, Kasahara Y, Hoshino H, Okuda T, Obika S. Systematic Analysis of 2′-O-Alkyl Modified Analogs for Enzymatic Synthesis and Their Oligonucleotide Properties. Molecules. 2023 Dec 2;28(23):7911. doi: 10.3390/molecules28237911.
Shell protein composition specified by the lncRNA NEAT1 domains dictates the formation of paraspeckles as distinct membraneless organelles.Nat Cell Biol. Hiro Takakuwa , Tomohiro Yamazaki , Sylvie Souquere , Shungo Adachi , Hyura Yoshino , Naoko Fujiwara , Tetsuya Yamamoto , Tohru Natsume , Shinichi Nakagawa , Gerard Pierron , Tetsuro Hirose .2023 Nov;25(11):1664-1675. doi: 10.1038/s41556-023-01254-1
Identification of invasive subpopulations using spatial transcriptome analysis in thyroid follicular tumors. Ayana Suzuki , Satoshi Nojima, Shinichiro Tahara , Daisuke Motooka, Masaharu Kohara, Daisuke Okuzaki, Mitsuyoshi Hirokawa, Eiichi Morii. J Pathol Transl Med. 2024 Jan;58(1):22-28. DOI: 10.4132/jptm.2023.11.21
Hayashida M, Suzuki R, Horie S, Masuda J, Yamaguchi T, Obika S. Applicabilityof supercritical fluid chromatography for oligonucleotide analysis: A proof-of-concept study. J Chromatogr A. 2023 Oct 11;1708:464333. doi:10.1016/j.chroma.2023.464333.
Functional domains of nuclear long noncoding RNAs: Insights into gene regulation and intracellular architecture.Obuse C, Hirose T.Curr Opin Cell Biol. 2023 Oct 6;85:102250. doi: 10.1016/j.ceb.2023.102250.
Analysis of splicing abnormalities in the white matter of myotonic dystrophy type 1 brain using RNA sequencing.
Yoshizumi K, Nishi M, Igeta M, Nakamori M, Inoue K, Matsumura T, Fujimura H, Jinnai K, Kimura T. Neurosci Res. 2023 Oct 6:S0168-0102(23)00192-X. doi:10.1016/j.neures.2023.10.002. Online ahead of print. PMID: 37806497
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, Leib DE, Chen R, Tanaka H, Mason AG, Lévesque D, Khan M, Razzaghi M, Prasolava T, Lanni S, Sato N, Caron MC, Panigrahi GB, Wang P, Lau R, Castel AL, Masson JY, Tippett L, Turner C, Spies M, La Spada AR, Campos EI, Curtis MA, Boisvert FM, Faull RLM, Davidson BL, Nakamori M, Okazawa H, Wold MS, Pearson CE. Cell. 2023 Oct 5:S0092-8674(23)01030-9. doi:10.1016/j.cell.2023.09008
Yuta Kanai,Misa Onishi,Yukino Yoshida,Tomohiro Kotaki,Shohei Minami,Ryotaro Nouda,Moeko Yamasaki,Yasutaka Enoki,Takeshi Kobayashi. Genetic engineering strategy for generating a stable dsRNA virus vector using a virus-like codon-modified transgene. J Virol. 2023 Sep 21:e0049223. doi: 10.1128/jvi.00492-23. Online ahead of print.
Tumor heterogeneity from the viewpoint of pathologists.Morii E. Pathol Int. 2023 Sep;73(9):394-405. doi: 10.1111/pin.13366. Epub 2023 Aug 28. PMID: 37638598 Review.
Takuya Kubo,Eisuke Kanao,Koki Ishida,Shohei Minami,Tetsuya Tanigawa,Ryosuke Mizuta,Yoshihiro Sasaki,Koji Otsuka,Takeshi Kobayashi. Efficient Selective Adsorption of SARS-CoV-2 via the Recognition of Spike Proteins Using an Affinity Spongy Monolith. Anal Chem. 2023 Sep 5;95(35):13185-13190. doi: 10.1021/acs.analchem.3c02097. Epub 2023 Aug 23.
Replication dynamics identifies the folding principles of the inactive X chromosome.Poonperm R, Ichihara S, Miura H, Tanigawa A, Nagao K, Obuse C, Sado T, Hiratani I. Nat Struct Mol Biol. 2023 Aug;30(8):1224-1237. doi: 10.1038/s41594-023-01052-1.
Mikami A, Mori S, Osawa T, Obika S. Post-Synthetic Nucleobase Modification of Oligodeoxynucleotides by Sonogashira Coupling and Influence of Alkynyl Modifications on the Duplex-Forming Ability. Chemistry. 2023 Aug 27:e202301928. doi: 10.1002/chem.202301928.
Yamaguchi T, Horie N, Aoyama H, Kumagai S, Obika S. Mechanism of the extremely high duplex-forming ability of oligonucleotides modified with N-tert-butylguanidine- or N-tert-butyl-N’- methylguanidine-bridged nucleic acids.Nucleic Acids Res. 2023 Aug 25;51(15):7749-7761. doi: 10.1093/nar/gkad608.
Deep Learning-Based Differential Diagnosis of Follicular Thyroid Tumors Using Histopathological Images.
Nojima S, Kadoi T, Suzuki A, Kato C, Ishida S, Kido K, Fujita K, Okuno Y, Hirokawa M, Terayama K, Morii E. Mod Pathol. 2023 Jul 31;36(11):100296. doi: 10.1016/j.modpat.2023.100296. Online ahead of print. PMID: 37532181
Miyake K, Costa Cruz PH, Nagatomo I, Kato Y, Motooka D, Satoh S, Adachi Y, Takeda Y, Kawahara Y, Kumanogoh A. A cancer-associated METTL14 mutation induces aberrant m6A modification affecting tumor growth. Cell Rep. 2023 Jul 25;42(7):112688. doi: 10.1016/j.celrep.2023.112688.
Taichiro Iki,Shinichi Kawaguchi,Toshie Kai. miRNA/siRNA-directed pathway to produce noncoding piRNAs from endogenous protein-coding regions ensures Drosophila spermatogenesis. Science Advances. 2023 July 21;9(29):eadh0397. doi: 10.1126/sciadv.adh0397
Chao Zeng , Takeshi Chujo , Tetsuro Hirose , Michiaki Hamada . Landscape of semi-extractable RNAs across five human cell lines. Nucleic Acids Research. 19 July 2023. doi:10.1093/nar/gkad567
Shohei Minami,Naomi Matsumoto,Hiroko Omori,Yutaka Nakamura,Shigeyuki Tamiya,Ryotaro Nouda,Jeffery A Nurdin,Moeko Yamasaki,Tomohiro Kotaki,Yuta Kanai,Toru Okamoto,Taro Tachibana,Hiroshi Ushijima,Takeshi Kobayashi,Shintaro Sato. Effective SARS-CoV-2 replication of monolayers of intestinal epithelial cells differentiated from human induced pluripotent stem cells. Sci Rep. 2023 Jul 18;13(1):11610. doi:0.1038/s41598-023-38548-1.
Chiba K, Yamaguchi T, Obika S. Development of 8-17 XNAzymes that are functional in cells. Chem Sci. 2023 Jun 28;14(28):7620-7629. doi:10.1039/d3sc01928d.
Miyake K, Costa Cruz PH, Nagatomo I, Kato Y, Motooka D, Satoh S, Adachi Y, Takeda Y, Kawahara Y, Kumanogoh A. A cancer-associated METTL14 mutation induces aberrant m6A modification affecting tumor growth. Cell Reports. 2023 in press.Doi:10.1016/j.celrep.2023.112688
Sheikh Ariful Hoque,Tomohiro Kotaki,Ngan Thi Kim Pham,Yuko Onda,Shoko Okitsu,Shintaro Sato,Yoshikazu Yuki,Takeshi Kobayashi,Niwat Maneekarn,Hiroshi Kiyono,Satoshi Hayakawa,Hiroshi Ushijima. Genotype Diversity of Enteric Viruses in Wastewater Amid the COVID-19 Pandemic. Food Environ Virol. 2023 Jun;15(2):176-191. doi: 10.1007/s12560-023-09553-4. Epub 2023 Apr 14.
Ovarian high-grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance.
Kido K, Nojima S, Motooka D, Nomura Y, Kohara M, Sato K, Ohshima K, Tahara S, Kurashige M, Umeda D, Takashima T, Kiyokawa H, Ukon K, Matsui T, Okuzaki D, Morii E.J Pathol. 2023 May;260(1):56-70. doi: 10.1002/path.6064.
Xing Y, Nakahama T, Wu Y, Inoue M, Kim JI, Todo H, Shibuya T, Kato Y, Kawahara Y. RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing . J Biol Chem. 2023 online ahead of publication. doi: 10.1016/j.jbc.2023.104840.
Kitamura A, Jiayue C, Suwa T, Kato Y, Wada T, Watanabe H. Neonatal administration of synthetic estrogen, diethylstilbestrol to mice up-regulates inflammatory Cxclchemokines located in the 5qE1 region in the vaginal epithelium. PLoS One. 2023 Mar 16;18(3):e0280421. doi: 10.1371/journal.pone.0280421.
Sawamoto H, Sasaki T, Takegawa-Araki T, Utsugi M, Furukawa H, Hirakawa Y, Yamairi F, Kurita T, Murahashi K, Yamada K, Ohta T, Kumagai S, Takemiya A, Obika S, Kotera J, Synthesis and properties of a novel modified nucleic acid, 2′-N-methanesulfonyl-2′-amino-locked nucleic acid, Bioorg Med Chem Lett. 2023 May 15;88:129289. doi: 10.1016/j.bmcl.2023.129289.
Dominant-negative variants in CBX1 cause a neurodevelopmental disorder.
Kuroda Y, Iwata-Otsubo A, Dias KR, Temple SEL, Nagao K, De Hayr L, Zhu Y, Isobe SY, Nishibuchi G, Fiordaliso SK, Fujita Y, Rippert AL, Baker SW, Leung ML, Koboldt DC, Harman A, Keena BA, Kazama I, Subramanian GM, Manickam K, Schmalz B, Latsko M, Zackai EH, Edwards M, Evans CA, Dulik MC, Buckley MF, Yamashita T, O’Brien WT, Harvey RJ, Obuse C, Roscioli T, Izumi K.Genet Med. 2023 Apr 20:100861. doi: 10.1016/j.gim.2023.100861. Online ahead of print.PMID: 370876352
Takakusa H, Iwazaki N, Nishikawa M, Yoshida T, Obika S, Inoue T, Drug Metabolism and Pharmacokinetics of Antisense Oligonucleotide Therapeutics: Typical Profiles, Evaluation Approaches, and Points to Consider Compared with Small Molecule Drugs, Nucleic Acid Ther. 2023 Apr;33(2):83-94. doi: 10.1089/nat.2022.0054
Souidi A, Nakamori M, Zmojdzian M, Jagla T, Renaud Y, Jagla K. Deregulations of miR-1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1. EMBO Rep. 2023 Apr 5;24(4):e56616. doi: 10.15252/embr.202256616. Epub 2023 Feb 28.
Nakahama T, Kawahara Y. The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways. Int Immunol. 2023 Mar 14;35(3):123-133. doi: 10.1093/intimm/dxac056.
Tanaka Y, Tanioku Y, Nakayama T, Aso K, Yamaguchi T, Kamada H, Obika S, Synthesis of multivalent fatty acid-conjugated antisense oligonucleotides: Cell internalization, physical properties, and in vitro and in vivo activities, Bioorg Med Chem. 2023 Mar 1;81:117192. doi: 10.1016/j.bmc.2023.117192.
Togawa H, Okubo T, Nonaka Y, Yamaguchi T, Obika S, Retention behavior of short double-stranded oligonucleotide and its potential impurities by anion-exchange chromatography under non-denaturing conditions, J Chromatogr A. 2023 Feb 22;1691:463808. doi: 10.1016/j.chroma.2023.463808.
Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast.
Hirano Y, Kinugasa Y, Kubota Y, Obuse C, Haraguchi T, Hiraoka Y.J Biochem. 2023 Feb 17:mvad017. doi: 10.1093/jb/mvad017. Online ahead of print.PMID: 367994443
Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine.
Morii E, Hatanaka Y, Motoi N, Kawahara A, Hamakawa S, Kuwata T, Nagatomo T, Oda Y, Okamoto A, Tanaka R, Iyoda A, Ichiro M, Matsuo Y, Nakamura N, Nakai T, Fukuhara M, Tokita K, Yamaguchi T, Takenaka M, Kawabata A, Hatanaka KC, Tsubame K, Satoh Y; Working Group on Cytology in the Era of Genomic Medicine. Pathobiology. 2023 Feb 8:1-23. doi: 10.1159/000528346.
Yamasaki M,Kanai Y, Wakamura Y, Kotaki T, Minami S, Nouda R, Jeffery A. N., Kobayashi T. Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis. J Virol. 2023 Jan 31;97(1):e01397-22. doi: 10.1128/jvi.01397-22. Epub 2023 Jan 5.
Jeffery A. N., Kotaki T, Kawagishi T, Sato S, Yamasaki M, Nouda R, Minami S, Kanai Y, Kobayashi T. N-glycosylation of rotavirus NSP4 protein affects viral replication and pathogenesis. J Virol. 2023 Jan 31;97(1):e01861-22. doi: 10.1128/jvi.01861-22. Epub 2023 Jan 4.
In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma.
Taniguchi S, Matsui T, Kimura K, Funaki S, Miyamoto Y, Uchida Y, Sudo T, Kikuta J, Hara T, Motooka D, Liu YC, Okuzaki D, Morii E, Emoto N, Shintani Y, Ishii M. Nat Commun. 2023 Jan 17;14(1):143. doi: 10.1038/s41467-022-35701-8.
Yoshida M, Oda C, Mishima K, Tsuji I, Obika S, Shimojo M, An antisense amido-bridged nucleic acid gapmer oligonucleotide targeting SRRM4 alters REST splicing and exhibits anti-tumor effects in small cell lung cancer and prostate cancer cells, Cancer Cell Int. 2023 Jan 17;23(1):8. doi: 10.1186/s12935-022-02842-1.
Takegawa-Araki T, Yasukawa K, Iwazaki N, Utsugi M, Furukawa H, Kumagai S, Sawamoto H, Obika S, 2′-N-Alkylaminocarbonyl-2′-amino-LNA: Synthesis, duplex stability, nuclease resistance, and in vitro anti-microRNA activity, Bioorg Med Chem. 2023 Jan 15;78:117148. doi: 10.1016/j.bmc.2022.117148
Rahman Chowdhury T, Taufiq T, Ishida K, Ariful Islam M, Kasahara Y, Osawa T, Obika S, Synthesis and biophysical properties of tetravalent PEG-conjugated antisense oligonucleotide,Bioorg Med Chem. 2023 Jan 15;78:117149. doi: 10.1016/j.bmc.2022.117149.
Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages.
Masui O, Corbel C, Nagao K, Endo TA, Kezuka F, Diabangouaya P, Nakayama M, Kumon M, Koseki Y, Obuse C, Koseki H, Heard E.Nat Cell Biol. 2023 Jan;25(1):134-144. doi: 10.1038/s41556-022-01047-y. Epub 2023 Jan 12.PMID: 366355054
Sakurai Y, Yamaguchi T, Yoshida T, Horiba M, Inoue T, Obika S, Synthesis and Properties of Nucleobase-Sugar Dual Modified Nucleic Acids: 2′-OMe-RNA and scpBNA Bearing a 5-Hydroxycytosine Nucleobase, J Org Chem. 2023 Jan 6;88(1):154-162. doi: 10.1021/acs.joc.2c02038.
Quantitative Microscopic Observation of Base-Ligand Interactions via Hydrogen Bonds by Single-Molecule Counting, Takashima, Y.; Komoto, Y.; Ohshiro, T. Nakatani, K.; Taniguchi, M. J. Am. Chem. Soc.2023, 145, 1310-1318. doi: 10.1021/jacs.2c11260.
A small molecule binding to TGGAA pentanucleotide repeats that cause spinocerebellar ataxia type 31, Shibata, T.; Nakatani, K. Bioorg. Med. Chem. Lett. 2022, 79, 129082. doi: 10.1016/j.bmcl.2022.129082.
Inhibitory Effects of Mismatch Binding Molecule on the Repair Reaction of Uracil-containing DNA, Ulhusna, A.; Murata, A.; Nakatani, K. Biochemistry 2022, 61, 2522-2530. doi: 10.1021/acs.biochem.2c00344.
2022
Hamajima R, Tina L., Minami S, Nouda R, Jeffery A. N., Yamasaki M, Kobayashi N, Kanai Y, Kobayashi T. A reverse genetics system for human rotavirus G2P[4]. J Gen Virol. 2022 Dec;103(12):001816. doi: 10.1099/jgv.0.001816.
RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.Commun Biol. 2022 Dec 28;5(1):1420. doi: 10.1038/s42003-022-04369-7.PMID: 36577784 Free PMC article.
Tumor cell plasticity in endometrioid carcinoma is regulated by neuronal membrane glycoprotein M6-b.
Kusumoto S, Ikeda JI, Kurashige M, Maeno-Fujinami E, Tahara S, Matsui T, Nojima S, Okuzaki D, Morii E. Oncol Lett. 2022 Dec 14;25(2):45. doi: 10.3892/ol.2022.13631.
Takegawa-Araki T, Yasukawa K, Iwazaki N, Maruyama H, Furukawa H, Sawamoto H, Obika S,Parallel synthesis of oligonucleotides containing N-acyl amino-LNA and their therapeutic effects as anti-microRNAs, Org Biomol Chem. 2022 Dec 7;20(47):9351-9361. doi: 10.1039/d2ob01809h.
Osawa T, Ren Q, Obika S, Development of Phosphoramidite Reagents for the Synthesis of Base-Labile Oligonucleotides Modified with a Linear Aminoalkyl and Amino-PEG Linker at the 3′-End, Molecules. 2022 Dec 3;27(23):8501. doi: 10.3390/molecules27238501.
Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding, Takashima, Y.; Murata, A.; Iida, K.; Sugai, A.; Hagiwara, M. and Nakatani, K. ACS Chem. Biol. 2022, 17, 2817-2827.doi: 10.1021/acschembio.2c00452.
Kato Y, Watanabe H. The mechanism for establishing the binary sex with environmental signals in the crustacean Daphnia magna. In: Tanaka, M., Tachibana, M. (eds) Spectrum of Sex. Springer, Singapore. 2022 Nov pp.203-219 doi: 10.1007/978-981-19-5359-0_12
Yamaji R, Nakagawa O, Kishimoto Y, Fujii A, Matsumura T, Nakayama T, Kamada H, Osawa T, Yamaguchi T, Obika S, Synthesis and physical and biological properties of 1,3-diaza-2-oxophenoxazine-conjugated oligonucleotides,Bioorg Med Chem. 2022 Oct 15;72:116972. doi: 10.1016/j.bmc.2022.116972.
Sugihara R, Kato Y, Mori T, Kawahara Y. Alignment of single-cell trajectory trees with CAPITAL. Nat Commun. 2022 Oct 14;13(1):5972. doi: 10.1038/s41467-022-33681-3.
Tirta YK, Adachi S, Perez CAG, Adhitama N, Nong QD, Natsume T, Kato Y, Watanabe H. CELF1 represses Doublesex1 expression via its 5′ UTR in the crustacean Daphnia magna. PLoS One. 2022 Oct 14;17(10):e0275526. doi: 10.1371/journal.pone.0275526.
Ogawa K, Yamada K, Etoh T, Kitagawa M, Shirasaka Y, Noguchi K, Kobayashi T, Nishizono A, Inomata M. Development of an Oncolytic Mammalian Orthoreovirus Expressing the Near-Infrared Fluorescent Protein iRFP720. Journal of Virological Methods, 2022, Oct;308:114574.doi: 10.1016/j.jviromet.2022.114574.
Ngan T. K. P., Nishimura S, Shimizu-Onda Y, Quang D. T., Komine-Aizawa S , Pattara K., Okitsu S , Sato S, Kobayashi T, Niwat M., Hayakawa S, Ushijima H. Emerging norovirus GII.4 Sydney[P31] causing acute gastroenteritis outbreak in children in Japan, during COVID-19, 2021. J Infect Chemother, 2022 Sep;28(9):1347-1351. doi: 10.1016/j.jiac.2022.05.015.
Nojima S, Ishida S, Terayama K, Matsumoto K, Matsui T, Tahara S, Ohshima K, Kiyokawa H, Kido K, Ukon K, Yoshida SY, Mitani TT, Doki Y, Mizushima T, Okuno Y, Susaki EA, Ueda HR, Morii E. A Novel Three-Dimensional Imaging System Based on Polysaccharide Staining for Accurate Histopathological Diagnosis of Inflammatory Bowel Diseases. Cell Mol Gastroenterol Hepatol. 2022;14(4):905-924. doi: 10.1016/j.jcmgh.2022.07.001.
Yamada, T.; Furuita, K.; Sakurabayashi, S.; Nomura, M.; Kojima, C.; and Nakatani, K. NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA. Nucleic Acids Res. 2022 Sep 12:gkac740. doi: 10.1093/nar/gkac740.
Yamazaki T, Yamamoto T, Hirose T. Micellization: A new principle in the formation of biomolecular condensates. Front Mol Biosci. 2022 Aug 29;9:974772. doi: 10.3389/fmolb.2022.974772.
Yamamoto T, Yamazaki T, Hirose T. Triblock copolymer micelle model of spherical paraspeckles. Front Mol Biosci. 2022 Aug 22;9:925058. doi: 10.3389/fmolb.2022.925058.
Matsushita M, Fujita K, Hatano K, Hayashi T, Kayama H, Motooka D, Hase H, Yamamoto A, Uemura T, Yamamichi G, Tomiyama E, Koh Y, Kato T, Kawashima A, Uemura M, Nojima S, Imamura R, Mubeen A, Netto GJ, Tsujikawa K, Nakamura S, Takeda K, Morii E, Nonomura N. High-fat diet promotes prostate cancer growth through histamine signaling. Int J Cancer. 2022 Aug 15;151(4):623-636. doi: 10.1002/ijc.34028.
Onishi T, Takashima T, Kurashige M, Ohshima K, Morii E. Mutually exclusive expression of EZH2 and H3K27me3 in non-small cell lung carcinoma. Pathol Res Pract. 2022 Aug 12;238:154071. doi: 10.1016/j.prp.2022.154071.
Nakatsubo D, Maeda Y, Hosokawa K, Kawada S, Okamoto M, Shimagami H, Tada T, Kiyokawa H, Sato K, Tahara S, Morii E, Narazaki M, Kumanogoh A, A case of relapsing polychondritis localized to the laryngeal cartilage in which FDG-PET/CT was helpful for diagnosis. Scand J Rheumatol 2022 Aug 10;1-3. doi: 10.1080/03009742.2022.2103937.
Matsui T, Iwasa A, Mimura M, Taniguchi S, Sudo T, Uchida Y, Kikuta J, Morizono H, Horii R, Motoyama Y, Morii E, Ohno S, Kiyota Y, Ishii M. Label-free multiphoton excitation imaging as a promising diagnostic tool for breast cancer. Cancer Sci. 2022 Aug;113(8):2916-2925. doi: 10.1111/cas.15428.
Ichihara S, Nagao K, Sakaguchi T, Obuse C, Sado T. SmcHD1 underlies the formation of H3K9me3 blocks on the inactive X chromosome in mice. Development. 2022 Aug 1; 149(15): dev200864. doi: 10.1242/dev.200864.
Tsuchihashi K, Miyoshi N, Fujino S, Kitakaze M, Ohue M, Danno K, Nakamichi I, Ohshima K, Morii E, Uemura M, Doki Y, Eguchi H. Risk Factors for Predicting Lymph Node Metastasis in Submucosal Colorectal Cancer. J Anus Rectum Colon. 2022 Jul 28;6(3):181-189. doi: 10.23922/jarc.2022-002.
Yoshida T, Morihiro K, Naito Y, Mikami A, Kasahara Y, Inoue T, Obika S. Identification of nucleobase chemical modifications that reduce the hepatotoxicity of gapmer antisense oligonucleotides. Nucleic Acids Res. 2022 Jul 22;50(13):7224-7234. doi: 10.1093/nar/gkac562.
Yasumizu Y, Ohkura N, Murata H, Kinoshita M, Funaki S, Nojima S, Kido K, Kohara M, Motooka D, Okuzaki D, Suganami S, Takeuchi E, Nakamura Y, Takeshima Y, Arai M, Tada S, Okumura M, Morii E, Shintani Y, Sakaguchi S, Okuno T, Mochizuki H. Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma. Nat Commun. 2022 Jul 22;13(1):4230. doi: 10.1038/s41467-022-31951-8.
Yamasaki T, Horie T, Koyama S, Nakao T, Baba O, Kimura M, Sowa N, Sakamoto K, Yamazaki K, Obika S, Kasahara Y, Kotera J, Oka K, Fujita R, Sasaki T, Takemiya A, Hasegawa K, Minatoya K, Kimura T, Ono K. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways. Sci Rep. 2022 Jul 14;12(1):11984. doi: 10.1038/s41598-022-16017-5.
Wu Y, Li P, Liu L, Goodwin AJ, Halushka PV, Hirose T, Nakagawa S, Zhou J, Liu M, Fan H. lncRNA Neat1 regulates neuronal dysfunction post-sepsis via stabilization of hemoglobin subunit beta. Mol Ther. 2022 Jul 6;30(7):2618-2632. doi: 10.1016/j.ymthe.2022.03.011.
Fukada A, Takahashi T, Kurokawa Y, Asaoka T, Teranishi R, Saito T, Yamamoto K, Yamashita K, Tanaka K, Makino T, Nakajima K, Umeda D, Morii E, Hirota S, Eguchi H, Doki Y. Laparoscopic resection for recurrent gastrointestinal stromal tumors and paraganglioma in a patient with Carney-Stratakis syndrome: A case report. Asian J Endosc Surg. 2022 Jul 6. doi: 10.1111/ases.13104.
Kubo A, Tanei T, R Pradipta A, Morimoto K, Fujii M, Sota Y, Miyake T, Kagara N, Shimoda M, Naoi Y, Motoyama Y, Morii E, Tanaka K, Shimazu K. Comparison of “click-to-sense” assay with frozen section analysis using simulated surgical margins in breast cancer patients. Eur J Surg Oncol. 2022 Jul;48(7):1520-1526. doi: 10.1016/j.ejso.2022.04.003.
Samejima H, Ose N, Sakurai T, Nagata H, Morii E, Shintani Y. G-CSF-producing left lung squamous cell carcinoma positive for ROS1 rearrangements completely resected after neoadjuvant radiation chemotherapy: A case report. Respir Med Case Rep. 2022 Jun 27;38:101697. doi: 10.1016/j.rmcr.2022.101697.
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